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You surely know that protein is made up of amino acids. There are 20 amino acids found in just about all dietary protein sources.\u00a0 One of these amino acids is phenylalanine (Phe) that must be carefully controlled and limited in the PKU diet (I know you know this, too, but don\u2019t stop reading yet; I\u2019ll get to some interesting new information soon\u2026).<\/p>\n
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Not all Proteins are created equal<\/strong><\/p>\n Amino acids can be grouped into two categories: Essential amino acids<\/strong> and Non-Essential amino acids<\/strong>. The simple difference is that your body can \u2018create\u2019 Non-Essential amino acids from other things in your diet, but cannot do so for Essential amino acids.<\/p>\n There is another group called Large Neutral Amino Acids (LNAAs)<\/strong>. Research suggests the presence of LNAAs can interfere with the \u2018transport\u2019 of Phe into your blood stream and then again from your blood stream into your brain. And that is obviously a good thing for PKUers.<\/p>\n But, if LNAAs help even a little bit, might that be a good thing? If so, might it make sense to choose a PKU medical food with a higher percentage of LNAAs? Here is a comparison of some of the formulas for PKU, both GMP based and AA based.<\/p>\n In this part of the BLOG I am not looking at specific amino acids, but how individual amino acid is actually \u2018born\u2019. After all, they don\u2019t grow on trees\u2026 so, where do they come from?\u00a0 It depends.<\/p>\n There are three ways to make amino acids: Chemical Synthesis, Human Hair \/ Animal Extraction, or Natural Fermentation. I am pretty sure I know which one you prefer, but allow me a moment to explain just a bit more about each.<\/p>\n <\/p>\n <\/p>\n Fermentation is the most natural way to make amino acids – It might cost more than the human hair or chemical synthesis approaches, but I\u2019d say it is worth it!<\/p>\n Chemical synthesis and the hair\/feather extraction techniques are generally produced overseas \u2013 China has a thriving business in these techniques.<\/p>\n The founders of Cambrooke had a choice when making medical food formulas for their two children with PKU \u2013 they opted to pursue a path leading to Cambrooke having the most natural and pure sources of amino acids in the Gytactin family of PKU formulas. Yes, these formulas use glycomacropeptide (GMP) for most of the protein, but also must sparingly include some amino acids.\u00a0 Cambrooke proudly uses Ajinomoto amino acids from its AjiPURE<\/strong> brand. These are made in the United States and are 100% naturally fermented.<\/p>\n When combined with Cambrooke\u2019s special GMP, Glytactin is the most natural and pure source of PKU protein available.<\/em><\/strong><\/p>\n Glycomacropeptide (GMP) is a modern day miracle when it comes to PKU protein nutrition. GMP starts as cow\u2019s milk. Milk is made of casein and whey. Some very smart scientists at the University of Wisconsin (lots of cows and cheese up there) discovered a part of whey called glycomacropeptide was naturally free of the aromatic amino acids including Phe\u2026<\/p>\n If only it were possible to separate PURE GMP from Whey protein. It is not (not yet anyhow). There is a complicated filtering process employed to separate GMP from whey and it is not perfect. As a result, there is some Phe \u2018residual\u2019 in the GMP used in PKU formulas. That\u2019s why you see Phe listed on the nutrition panel of all medical food formulas containing GMP. HOWEVER \u2013 not all GMP is equal.<\/p>\n Since being acquired by Ajinomoto, Cambrooke has been able to introduce PKU formulas with a more purified GMP. More pure = less Phe. The newest Cambrooke PKU formulas have less Phe\u00a0than what some consider \u2018free foods\u2019 in terms of the phe content. At a level as low as 1 mg PHE per gram of Protein, a 10 gram of protein equivalent of the new Cambrooke Glytactin medical foods have only 10 mg of phe \u2013 that\u2019s less than an apple!<\/p>\n We think that is awesome and opens up more options for your diet as well as may allow highly Phe-sensitive PKUers to also enjoy the natural taste of GMP protein. By the way, these new formulas are called Glytactin RTD Lite and Glytactin BUILD. Of course, your health care professional must be consulted with regard to changing to a Cambrooke Glytactin GMP formula.\u00a0 If you get the green light, then we are here and ready to help.<\/p>\n Today\u2019s BLOG is all about protein \u2013 with special focus on advancements in many new Cambrooke Glytactin products in terms of purity. Phe reduction (aka purity) as well as overall natural protein power. Key things you will learn if you read on: The amino acids used in some PKU formulas may lower purity depending on […]<\/p>\n","protected":false},"author":8,"featured_media":1484,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69],"tags":[68,50],"class_list":["post-1456","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-formula","tag-cambrooke","tag-pku"],"featured_image_src":{"landsacpe":["https:\/\/www.cambrooke.com\/blog\/wp-content\/uploads\/2018\/12\/Natural_GMP-1000x445.png",1000,445,true],"list":["https:\/\/www.cambrooke.com\/blog\/wp-content\/uploads\/2018\/12\/Natural_GMP-463x348.png",463,348,true],"medium":["https:\/\/www.cambrooke.com\/blog\/wp-content\/uploads\/2018\/12\/Natural_GMP-500x375.png",500,375,true],"full":["https:\/\/www.cambrooke.com\/blog\/wp-content\/uploads\/2018\/12\/Natural_GMP-e1547589113444.png",600,450,false]},"_links":{"self":[{"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/posts\/1456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/comments?post=1456"}],"version-history":[{"count":10,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/posts\/1456\/revisions"}],"predecessor-version":[{"id":1473,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/posts\/1456\/revisions\/1473"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/media\/1484"}],"wp:attachment":[{"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/media?parent=1456"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/categories?post=1456"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cambrooke.com\/blog\/wp-json\/wp\/v2\/tags?post=1456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/www.cambrooke.com\/blog\/wp-content\/uploads\/2018\/12\/graph.png\")
<\/h4>\nNot all Amino Acids are created equal<\/strong><\/h4>\n
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Not all GMP is created equal<\/strong><\/h4>\n
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<\/p>\nCompared to other GMP-based medical foods, new Cambrooke Glytactin formulas have up to 40% less Phe.<\/em><\/strong><\/span><\/h3>\n
In the meantime, we will continue working on our mission to make you the very best medical foods to help you feel balanced and feel better.<\/em><\/strong><\/span><\/h3>\n","protected":false},"excerpt":{"rendered":"